Which condition is NOT associated with altering olfaction due to local infection?

The condition that does not significantly alter olfaction due to local infection is Parkinson's disease. While olfactory dysfunction can be a symptom in individuals with Parkinson's disease, this impairment primarily arises from neurodegenerative processes rather than a local infection.

In contrast, influenza, Sjögren's syndrome, and sinusitis can all directly affect the nasal passages and the surrounding areas, leading to changes in smell. Influenza often causes upper respiratory symptoms that can impair the olfactory system during the course of the infection. Sjögren's syndrome, an autoimmune condition, can lead to dryness in oral and nasal mucosa, potentially impacting the sense of smell. Sinusitis, an infection or inflammation of the sinus cavities, directly disrupts the olfactory receptors and can temporarily alter one’s sense of smell due to blockage and inflammation.

Therefore, while olfactory dysfunction may be observed in various diseases, Parkinson's disease is distinct in that its olfactory issues are driven more by the underlying neurodegenerative condition rather than an ongoing local infection.